Host research mentor: Didier Stainier, PhD, Professor, Department of Biochemistry and Biophysics, UCSF
The Stainier lab uses the zebrafish as a model to investigate vertebrate organ development. The lab is interested in understanding molecular events that drive processes such as cellular differentiation and morphogenesis. The zebrafish is an ideal model organism to study early embryological development. It grows quickly and provides clear resolution of single cells in any tissue during all developmental stages. Diabetes is a detrimental disease that affects more and more people each year. Because an understanding of pancreatic development is essential for developing a therapy for this disease, we are currently investigating the pathways that influence the regeneration of insulin secreting -cells. Previous research has implicated anti-histamines with an increased rate of -cell regeneration. My project deals with determining the effects of various anti-histamines on the known pathways of cell regeneration in the zebrafish.