Professor Pamela Denbesten, University of California, San Francisco

The Denbesten lab focuses on whole‐tooth regeneration, both for direct clinical application and as a model for organogenesis in general. A major hindrance to the goal of tooth regeneration is that Ameloblasts (the cells
responsible for secreting proteins which direct the formation of tooth enamel) are no longer present after teeth have erupted. My lab is currently engaged in efforts to identify the factors capable of promoting Ameloblast differentiation from human embryonic stem cells.